Lanthanide chelates as new fluorochrome labels for cytochemistry.
نویسندگان
چکیده
منابع مشابه
AMPED: a new platform for picolinate based luminescent lanthanide chelates.
The synthesis of a new nonacoordinating ligand based on an AMPED (6-amino-6-methylperhydro-1,4-diazepine) scaffold functionalized by three picolinate (6-carboxy-2-methylpyridine) arms is described. Coordination of lanthanide cations (Ln = Eu and Tb) was investigated by spectrophotometric titrations monitored by UV-Vis absorption and steady-state emission spectroscopy, showing the formation of [...
متن کاملCarbostyril derivatives as antenna molecules for luminescent lanthanide chelates.
Luminescent lanthanide complexes consisting of a lanthanide-binding chelate and organic-based antenna molecule have unusual emission properties, including millisecond excited state lifetimes and sharply spiked spectra, compared to standard organic fluorophores. We have previously used carbostyril (cs124, 7-amino-4-methyl-2(1H)-quinolinone) as an antenna molecule (Li and Selvin, J. Am. Chem. Soc...
متن کاملSynthesis and optical properties of macrocyclic lanthanide(III) chelates as new reagents for luminescent biolabeling.
The convenient and efficient synthesis of two macrocyclic ligands (15- and 18-membered) based on a dipyrido-6,7,8,9-tetrahydrophenazine (dpqc) or 2,2':6',2''-terpyridine (tpy) heterocycle and a DTTA (diethylenetriaminetriacetic acid) skeleton is described. In these ligands the DTTA skeleton contains an additional extracyclic functionality (NH(2) group) suitable for covalent attachment to bioact...
متن کاملNew 9- or 10-dentate luminescent lanthanide chelates.
Polyaminocarboxylate-based luminescent lanthanide complexes have unusual emission properties, including millisecond excited-state lifetimes and sharply spiked spectra compared to common organic fluorophores. There are three distinct sections in the structure of the luminescent lanthanide chelates: a polyaminocarboxylate backbone to bind the lanthanide ions tightly, an antenna molecule to sensit...
متن کاملLanthanide Chelates as a Tool in Nucleic Acid Chemistry
The potentiality of lanthanide chelates as photoluminescent markers and cleaving agents of nucleic acids is discussed, the main emphasis being on the chelates derived from aromatic nitrogen bases.
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ژورنال
عنوان ژورنال: Journal of Histochemistry & Cytochemistry
سال: 1988
ISSN: 0022-1554,1551-5044
DOI: 10.1177/36.11.3049792